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Poster display session: Breast cancer - early stage, locally advanced & metastatic, CNS tumours, Developmental therapeutics, Genitourinary tumours - prostate & non-prostate, Palliative care, Psycho-oncology, Public health policy, Sarcoma, Supportive care

5131 - Effect of yoga on Chemo-Radiotherapy induced Diabetes and Hypertension (CRID-H) among cervical cancer patients at a regional cancer institute in South India.

Date

22 Oct 2018

Session

Poster display session: Breast cancer - early stage, locally advanced & metastatic, CNS tumours, Developmental therapeutics, Genitourinary tumours - prostate & non-prostate, Palliative care, Psycho-oncology, Public health policy, Sarcoma, Supportive care

Presenters

Noopur Nelson

Citation

Annals of Oncology (2018) 29 (suppl_8): viii603-viii640. 10.1093/annonc/mdy300

Authors

N.K. Nelson1, I.A. Khaleel1, M. ROY2, R. C2, H.B. Govardhan3, N. Jasti2, S. Suresh2, R. Kashyap2, L. Lokanath2

Author affiliations

  • 1 Radiation oncology, Kidwai Cancer Institute, 560029 - Bengaluru/IN
  • 2 Radiation oncology, KIDWAI Memorial Institute of oncology, 560029 - Bangalore/IN
  • 3 Radiation oncology, Kidwai Memorial Institute of Oncology, 560029 - Bangalore/IN
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Resources

Abstract 5131

Background

Prior studies suggest the benefits of yoga in maintaining Diabetes and Hypertension. In this study we aim to evaluate the effect of yoga on Chemo-Radiotherapy induced Diabetes and Hypertension (CRID-H) in cervical cancer patients.

Methods

60 cervical cancer subjects (stage II - IV) undergoing chemo-radiation therapy were randomized into yoga (n = 30) and control group (n = 30). Yoga group was given loosening, breathing, chanting and meditation for 5 days/ week for 6 weeks. Weekly assessment of Random Blood Sugar and blood pressure was recorded from baseline to discharge. Appropriate statistical analysis was conducted.

Results

6 yoga and 6 non-yoga patients were found to be known case of hypertension and on medications. During the course of chemo-radiation 4 yoga and 6 non-yoga patients developed hypertension. The systolic pressure among the yoga group remained constant with a mean difference of just 11.3mm of Hg while non-yoga group recorded 37.2mm of Hg Comparative analysis between the two groups show Systolic BP attained significance of p = 0.3 and Diastolic BP, p = 0.11. Diastolic BP in non-hypertensive patients of yoga group (p = 0.01) achieved good significance while hypertensive patients (p = 0.14) and all patients (p = 0.11) the results incline towards significance. Thus, yoga is effective to maintain BP among non-hypertensive patients and attain moderate control in hypertensive ones. RBS data reveals 5 yoga and 6 non-yoga subjects had pre-existing diabetes. 4 yoga and 6 non-yoga subjects developed diabetes with chemo-radiation by the 3rd week of treatment. Good significance was achieved between the two groups as a whole (p = 0.02). The difference was highly significant at p = 0.009 among pre-existing diabetic patients.

Conclusions

Adjuvant yoga therapy helps to control CRID-H in cervical cancer efficiently. The control achieved in RBS is highly significant. Considerable effect in hypertension was also observed. The above direction can be employed in future studies with larger sample size. Acknowledgement- Ministry of AYUSH, Government of India.

Clinical trial identification

Legal entity responsible for the study

Ministry of Ayush, Government of India.

Funding

Has not received any funding.

Editorial Acknowledgement

Disclosure

All authors have declared no conflicts of interest.

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