Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

Poster display session

4768 - The Relationship between Oral Supportive Care and Oral Complications in Cancer Patients Receiving Chemotherapy: A Retrospective Study

Date

10 Sep 2017

Session

Poster display session

Topics

Cytotoxic Therapy;  Supportive Care and Symptom Management

Presenters

Tomoko Kataoka

Citation

Annals of Oncology (2017) 28 (suppl_5): v543-v567. 10.1093/annonc/mdx388

Authors

T. Kataoka

Author affiliations

  • Dental Oncology, Kobe Minimally Invasive Cancer Center, 6500046 - Kobe/JP
More

Resources

Abstract 4768

Background

Oral supportive care for cancer patients received medical insurance coverage in 2012 in Japan. Management includes not only prevention of wound infection and perioperative pneumonia but also treatment of oral complications during chemotherapy and radiotherapy in cancer patients. We conducted a retrospective study to analyze the efficacy of oral supportive care for cancer patients receiving chemotherapy.

Methods

We retrospectively analyzed consecutive 1,142 cases received anticancer chemotherapy in our hospital from April 2013 to March 2017.

Results

Patients were 633 males and 509 females aged 23-92 years (median 66). Primary sites were lung in 246, esophagus in 193, breast in 137, head and neck in 112, and others in 454. Treatment was chemotherapy in 752, and concurrent chemoradiotherapy in 390. Before beginning chemotherapy, all patients received a dental check and acquired tooth brushing techniques. We compared the oral hygiene status in 752 patients before the beginning of therapy and at the 1-month check. Rates of improved, stable and regression status were 56.9%, 23.5%, and 19.6%. Regression appeared due to worsening of general condition, and also to oral mucositis among head and neck cancer patients. Oral supportive care was continued to maintain good oral hygiene, detect oral complications early and manage them with dental treatment, dental extraction, mechanical cleaning, medicine, mouthwash and topical ointment and analgesics. Oral complications of ≥ Grade 3 (NCI-CTC AE ver. 3.0) were antiresorptive agents-related osteonecrosis of the jaw, teeth infections, and oral mucositis occurred during treatment. There was a significant difference in the incidence of oral complications between more and less than 3 months from the latest dental visit at the start of chemotherapy (p 

Conclusions

Oral supportive care for cancer patients receiving chemotherapy should begin before the start of treatment and continue until the successful completion of treatment, especially for the deteriorated patients, head and neck cancer patients, and patients who did not receive dental checkups and cleaning for more than 3 months.

Clinical trial identification

Legal entity responsible for the study

Kobe Minimally Invasive Cancer Center

Funding

None

Disclosure

All authors have declared no conflicts of interest.

This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings
  • Necessary cookies enable core functionality. The website cannot function properly without these cookies, and you can only disable them by changing your browser preferences.