The 8th edition of the AJCC TNM staging system for gastric cancer was released in 2016 and included major revisions, especially of stage III. We aimed to compare the prognostic value of the seventh and eighth editions of the AJCC TNM classification for stage III gastric cancer.
Clinical data on 1,579 patients operated on for stage III gastric cancer according to the seventh edition between December 2006 and November 2014 were analyzed and the 7th and 8th TNM classifications were compared in terms of prognostic performance.
According to the 8th AJCC TNM classification, the 5-year overall survival rates of IIIA, IIIB and IIIC were 49.4%, 29.6% and 15.2%, respectively (P
The 8th TNM classification provide better accuracy than 7th edition in predicting the prognosis of stage III gastric cancer with LNs harvested≥30.
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All authors have declared no conflicts of interest.