Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

Poster display session

5013 - Risk of malignant mesothelioma in Spain from environmental asbestos exposure


10 Sep 2017


Poster display session


Cancers in Adolescents and Young Adults (AYA);  Cancer Prevention;  Mesothelioma


Junior Smith Torres-Roman


Annals of Oncology (2017) 28 (suppl_5): v511-v520. 10.1093/annonc/mdx385


J.S.S. Torres-Roman1, G. Lopez-Abente2, J.M. Sanz-Anquela3

Author affiliations

  • 1 Ica, Faculty of Medicine, Universidad Nacional San Luis Gonzaga, 11702 - Ica/PE
  • 2 Madrid, Cancer and Environmental Epidemiology Unit National Center for Epidemiology Carlos III Institute of Health. Madrid, SPAIN, Madrid - -/ES
  • 3 Madrid, Cancer Registry and Pathology Department Hospital Universitario Principe de Asturias Assoc. Prof. Health Sciences Department of Medicine and Medical Specialties University of Alcalá. Alcala de Henares, Madrid. Spain, -/ES


Abstract 5013


The link between malignant mesothelioma (MM), and asbestos exposure (AE), is very high. AE may have occupational or environmental non-occupational source. The highest levels of AE occur in the workplace and mainly affect men. However, environmental AE, affect men and women equally. As the occupational AE prevails over the environmental non-occupational, a sex-ratio < 2 alert of possible environmental AE. The objective of this study is to evaluate the spatio-temporal distribution of the sex-ratio, in order to identify those areas with possibly higher environmental AE.


We conducted an analysis of the 6,143,124 deaths in Spain during the period 2000–2015, looking for those deaths caused by MM. Information regarding sex, year of death, age at death, province, and cause of death (ICD-10) was extracted from the deceased registry of the National Institute of Statistics. We calculated the sex-ratio between the deceased by MM according to its distribution by provinces and years, and the ratio of mortality rates adjusted for age (European standard population). We also obtained the proportion of MM among the total deceased (MM per 10,000 deaths).


MM deaths were 5,345. Men 4,025 and women 1,329 (sex-ratio: 3.31). During the 2000- 2015 period the sex-ratio remained relatively stable, ranging from 2.21 in 2007 to 4.31 in 2005. In the years 2000 and 2015 the sex-ratio was 3.34 and 3.07, respectively. Likewise, in the years 2000 y 2015 the men/women age-adjusted rates was 2.83 and 3.93, respectively. The variations by provinces were more pronounced. The lowest sex-ratio (1.5) corresponded to the 140 deaths of Navarra and the highest (12.67), to the 41 deaths of Vitoria. Other low sex-ratio values were detected for Almeria (2,07), Donostia (2,02), Huesca (2) and Tarragona (1,97). Among these provinces with a possible higher environmental AE risk (sex-ratio equal to or 


The high provincial variability in Spain of the proportion of women who died of MM, makes necessary the carry out of new research focused in the provinces detected as with a possible greater risk of environmental asbestos exposure in the general population.

Clinical trial identification

Legal entity responsible for the study

Jose Miguel Sanz-Anquela; Junior Smith Torres-Roman




J.M. Sanz-Anquela: Occasionally has served as a consultant to the court, always at the request of plaintiff asbestos victims. All other authors have declared no conflicts of interest.

This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings
  • Necessary cookies enable core functionality. The website cannot function properly without these cookies, and you can only disable them by changing your browser preferences.