Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

Poster display session

3831 - Nomograms for pre- and postoperative prediction of long-term survival for patients of proximal gastric cancer: A large-scale,single-centre retrospective study

Date

09 Sep 2017

Session

Poster display session

Topics

Gastric Cancer

Presenters

Qiyue Chen

Citation

Annals of Oncology (2017) 28 (suppl_5): v209-v268. 10.1093/annonc/mdx369

Authors

Q. Chen, H. Chang-Ming, C. Zheng, P. Li, J. Xie

Author affiliations

  • Department Of Gastric Surgery, Fujian Medical University Union Hospital, 350001 - Fuzhou/CN
More

Resources

Abstract 3831

Background

The prognostic prediction for long-term survival for patients of proximal gastric cancer has not been well established.

Methods

Between December 2006 and June 2013, we prospectively collected and retrospectively analyzed the medical records of 746 patients with upper-third gastric cancer (GC). The data were split 75/25, with one group used for model development and the other group used for validation testing. COX regression was used to identify preoperative and postoperative risk factors associated with OS.

Results

Among the 746 patients examined, the 1-, 3- year overall survival rate is respectively: 89.4%, 66.1%. The preoperative T staging (cT), preoperative N staging (cN), ASA score, preoperative CA199, preoperative tumor size and the weight loss of 3-6 months were incorporated into the preoperative nomogram for overall survival (OS) prediction for the training set. In addition to these variables, LVI, postoperative tumor size, postoperative T stage, postoperative N stage, postoperative blood transfusion and postoperative complications were incorporated into the postoperative nomogram. All calibration curves for probability of OS fitted well. In the training cohort, the preoperative nomogram achieved a C-index of 0.751[95% confidence interval (CI) 0.732-0.770] in predicting OS and accurately stratified patients into 4 prognostic subgroups (5-year OS rates: 86.8%, 73.0%, 43.72% and 20.9%, P 

Conclusions

The 2 nomograms showed accurate pre- and postoperative prediction for long-term survival for patients of proximal gastric cancer.

Clinical trial identification

Legal entity responsible for the study

Changming Huang

Funding

None

Disclosure

All authors have declared no conflicts of interest.

This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings
  • Necessary cookies enable core functionality. The website cannot function properly without these cookies, and you can only disable them by changing your browser preferences.