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Poster display session

2572 - Febrile Neutropenia: a systematic review of the first 5 years of a cancer unit.


10 Sep 2017


Poster display session


Supportive Care and Symptom Management


Joao Pinto


Annals of Oncology (2017) 28 (suppl_5): v543-v567. 10.1093/annonc/mdx388


J. Pinto1, I. Leão2, F. Branco1, J. Godinho1, P. Simões1, F. Lopes1, A. Escária1, F. Costa1, I. Galvão1, J.L. Passos-Coelho1

Author affiliations

  • 1 Medical Oncology, Hospital Beatriz Angelo-Loures, 2674-514 - Loures/PT
  • 2 Medical Oncology, Centro Hospital Vila Nova de Gaia/Espinho, 4434-502 - V. N. Gaia/PT


Abstract 2572


Febrile Neutropenia (FN) is a potentially life-threatening and dose-limiting complication of myelosuppressive chemotherapy (CT) that often requires hospital admission (HA). Patients (pts) with FN must initiate antibiotic (atb) therapy promptly and delay in diagnosis and subsequent treatment are associated with higher mobility and mortality.


Retrospective single institution review of all FN episodes that occurred in the years 2012 to 2016 in pts with solid tumors with an absolute neutrophil count (ANC) 38 °C and ANC


Among 1.947 eligible pts, 152 had a NF (8%) with a total of 173 NF episodes. Median age was 67yo; 90 were males (59%). Median initial ANC was 310/µl, range 20-990 (


FN is a serious and common complication of CT treatment which must be diagnosed and treated rapidly. Delays in the evaluation of febrile cancer pts on systemic treatment may compromise the outcome of these pts.

Clinical trial identification

Legal entity responsible for the study

João Moreira Pinto




All authors have declared no conflicts of interest.

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