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Poster display session

2572 - Febrile Neutropenia: a systematic review of the first 5 years of a cancer unit.

Date

10 Sep 2017

Session

Poster display session

Topics

Supportive Care and Symptom Management

Presenters

Joao Pinto

Citation

Annals of Oncology (2017) 28 (suppl_5): v543-v567. 10.1093/annonc/mdx388

Authors

J. Pinto1, I. Leão2, F. Branco1, J. Godinho1, P. Simões1, F. Lopes1, A. Escária1, F. Costa1, I. Galvão1, J.L. Passos-Coelho1

Author affiliations

  • 1 Medical Oncology, Hospital Beatriz Angelo-Loures, 2674-514 - Loures/PT
  • 2 Medical Oncology, Centro Hospital Vila Nova de Gaia/Espinho, 4434-502 - V. N. Gaia/PT
More

Resources

Abstract 2572

Background

Febrile Neutropenia (FN) is a potentially life-threatening and dose-limiting complication of myelosuppressive chemotherapy (CT) that often requires hospital admission (HA). Patients (pts) with FN must initiate antibiotic (atb) therapy promptly and delay in diagnosis and subsequent treatment are associated with higher mobility and mortality.

Methods

Retrospective single institution review of all FN episodes that occurred in the years 2012 to 2016 in pts with solid tumors with an absolute neutrophil count (ANC) 38 °C and ANC

Results

Among 1.947 eligible pts, 152 had a NF (8%) with a total of 173 NF episodes. Median age was 67yo; 90 were males (59%). Median initial ANC was 310/µl, range 20-990 (

Conclusions

FN is a serious and common complication of CT treatment which must be diagnosed and treated rapidly. Delays in the evaluation of febrile cancer pts on systemic treatment may compromise the outcome of these pts.

Clinical trial identification

Legal entity responsible for the study

João Moreira Pinto

Funding

None

Disclosure

All authors have declared no conflicts of interest.

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