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Poster display session

1902 - Evaluation of Quality of Life in survivors with malignant pleural mesothelioma in Japan

Date

09 Sep 2017

Session

Poster display session

Topics

Mesothelioma

Presenters

Isao Oze

Citation

Annals of Oncology (2017) 28 (suppl_5): v568-v572. 10.1093/annonc/mdx389

Authors

I. Oze1, Y. Nagamatsu2, K. Aoe3, K. Hotta4, K. Kato5, J. Nakagawa6, K. Hara6, T. Kishimoto7, N. Fujimoto8

Author affiliations

  • 1 Division Of Molecular And Clinical Epidemiology, Aichi Cancer Center Research Institute, 464-8681 - Nagoya/JP
  • 2 College Of Nursing, St. Luke’s International University, Tokyo/JP
  • 3 Department Of Medical Oncology, National Hospital Organization Yamaguchi-Ube Medical Center, Ube/JP
  • 4 Center For Innovative Clinical Medicine, Okayama University Hospital, Okayama/JP
  • 5 Department Of Radiology, Kawasaki General Medical Center, Okayama/JP
  • 6 Department Of Nursing, Okayama Rosai Hospital, Okayama/JP
  • 7 Department Of Medicine, Okayama Rosai Hospital, Okayama/JP
  • 8 Department Of Medical Oncology, Okayama Rosai Hospital, Okayama/JP
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Resources

Abstract 1902

Background

Malignant pleural mesothelioma (MPM) is the malignancy with poor prognosis. Most patients with MPM present severe symptoms such as pain, dyspnea and fatigue. Because of the symptoms and poor prognosis, MPM survivors would have poor Quality of Life (QOL), however, their QOL has not been well evaluated.

Methods

Subjects were the survivors of MPM. We asked the cancer hospitals in Japan and MPM Patients' Association to distribute the self-administered questionnaire. QOL was evaluated using scales of the EORTC QLQ-C30 and QoQoLo short version. In addition to the QOL, clinical factors were collected using the questionnaire. Mean and its standard deviation were used to evaluate QOL scores. Wilcoxon rank sum test was used to compare the QOL scores. Factors affecting the QOL score were evaluated by multiple regression model.

Results

In total, 133 survivors with MPM participated in the study. Regarding the QOL evaluated by QLQ-C30: functional scales were poor (scores >50), while symptom scales were not so poor (scores 2 years from diagnosis, and female. Similarly, good PS and >2 years from diagnosis were the factors caused higher total score of CoQoLo core domein.

Conclusions

Survivors with MPM had physical and psychological difficulties. Even the survivors with good PS had functional difficulty. Individualized supports are required for survivors with MPM.

Clinical trial identification

Legal entity responsible for the study

Nobukazu Fujimoto

Funding

Ministry of Health, Labour and Welfare, Japan

Disclosure

All authors have declared no conflicts of interest.

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