A recent American Cancer Society study showed that the rate of colorectal cancer (CRC) in young American adults is rising. There are limited data on young Arabian adults with CRC. Herein we explore differences between American and Egyptian young adults with CRC.
A retrospective review of young (≤46 years old) patients (pts) with CRC in the United States (US-pts) and Egypt (EGY-pts) was undertaken. T and Fisher’s exact tests were used for comparative analyses. Kaplan-Meier methodology estimated survival.
In total, 504 pts with CRC were studied, incorporating 62 US-pts (median age 38 yrs, range 20-46) and 442 EGY-pts (35 yrs, 15-46). US-pts were more commonly female (66% vs 41%, p
Significant differences were observed among young US-pts and EGY-pts with CRC, particularly primary tumor location, patterns of metastasis, and treatment used. Further evaluation of the environmental and ethnic impact on disease biology and treatment outcomes is warranted.
Clinical trial identification
Legal entity responsible for the study
Georgetown University IRB
All authors have declared no conflicts of interest.