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Poster display session

2338 - Nutritional recovery after open and laparoscopic distal gastrectomy for early gastric cancer: A prospective multicenter comparative trial (CCOG1204)

Date

09 Sep 2017

Session

Poster display session

Presenters

Chie Tanaka

Citation

Annals of Oncology (2017) 28 (suppl_5): v209-v268. 10.1093/annonc/mdx369

Authors

C. Tanaka1, M. Kanda1, K. Misawa2, S. Ito3, Y. Ito3, Y. Mochizuki4, K. Ishigure5, T. Yaguchi6, J. Teramoto7, H. Nakayama8, Y. Kawase9, M. Fujiwara1, Y. Kodera1

Author affiliations

  • 1 Gastroenterological Surgery, Nagoya University, Graduate School of Medicine, 466-8550 - Nagoya/JP
  • 2 Department Of Gastroenterological Surgery, Aichi Cancer Center Chuo Hospital, 464 - Nagoya/JP
  • 3 Department Of Gastroenterological Surgery, Aichi Cancer Center Hospital, 4648681 - Nagoya/JP
  • 4 Department Of Surgery, Komaki Municipal Hospital, 485 - Komaki/JP
  • 5 Department Of Surgery, Konan Kosei Hospital, 483 - Konan/JP
  • 6 Department Of Surgery, Kainan Hospital, 498 - Yatomi/JP
  • 7 Department Of Surgery, Yokkaichi Municipal Hospital, 510 - Yokkaichi/JP
  • 8 Department Of Surgery, National Hospital Organization Nagoya Medical Center, 460 - Nagoya/JP
  • 9 Department Of Surgery, Tosei General Hospital, 489 - Seto/JP
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Resources

Abstract 2338

Background

Little information from prospective clinical trials is available on the influences of surgical approaches on postoperative body compositions and nutritional status. We designed a prospective non-randomized trial to compare postoperative chronological changes in body composition and nutritional status between laparoscopic and open distal gastrectomy for stage I gastric cancer (GC).

Methods

Body compositions and nutritional indicators in blood tests were measured at the baseline and at the 1st, 3rd, 6th and 12th postoperative months (POM). The primary endpoint was the decrease relative to the baseline in the body muscle mass at POM6.

Results

Ninety-six patients for the laparoscopic group and 52 for the open group were eligible for data analysis. No significant differences were found in any baseline demographics, body compositions and nutritional indicators between the groups. The changes of body muscle mass at POM 6 were similar in both groups. Overall, no significant differences between the groups were observed in any of the body composition and nutritional indicators during the first year after surgery.

Conclusions

Postoperative body compositions and nutritional status was not affected by surgical approaches during the first 12 months after surgery in patients who underwent distal gastrectomy for stage I GC.

Clinical trial identification

UMIN000015196

Legal entity responsible for the study

None

Funding

None

Disclosure

S. Ito: Personal fees from Olympus. Y. Kodera: Grants and personal fees from Johnson & Johnson, Covidien, and Otsuka Pharmaceutical Factory. All other authors have declared no conflicts of interest.

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