Negative lymph node (NLN) count has been validated as a protective predictor in various cancers after radical resection. However, the prognostic value of NLN count in the setting of gastric cancer patients who have received palliative resection has not been investigated. The aim of the present study was to explore the effect of NLN counts on the survival outcomes in patients with stage IV gastric cancer after palliative resection.
Surveillance, Epidemiology, and End Results Program (SEER)-registered gastric cancer patients were used for analysis in this study. Kaplan-Meier survival curves and multivariate Cox proportional hazards model were used to assess the risk factors for survival.
A total of 1,495 patients with stage IV gastric cancer underwent palliative resection were identified from SEER database between 2004 and 2011. It showed that NLN count (P < 0.001) and N stage (P
Our present study revealed that NLN count was an independent prognostic predictor in stage IV gastric cancer after palliative resection. Standard lymph node dissection, such as D2 lymphadectomy maybe still necessary during palliative resection for patients with metastatic gastric cancer.
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All authors have declared no conflicts of interest.