Cancer registration is the systematic collection of data about cancer and tumor diseases and is a valuable tool for understanding what causes cancer and how best to diagnose and treat it. In Greece, this data collection is managed only in the island of Crete, by the Cancer Registry of Crete (CRC;) . In this study, we present data on the cancer incidence and mortality for all neoplasms in Crete, during 1992-2013. Secondary objectives were to map the longitudinal trends of all MN and per type.
Data were obtained from the Cancer Registry of Crete which is the only population-based registry in Greece since 1992 (permanent residents=623.000). Data were coded according to the ICD-10O and included several parameters on demographics, medical history, and lifestyle factors. Age-standardized incidence/mortality/100,000/year (ASIR, ASMR) were estimated, while Bayesian models were performed to assess any longitudinal variations (a = 0.05).
ASIR and ASMR for all cancers in Crete were 302.8 and 150.5 respectively. Cancer of the lung and bronchus is the most common invasive cancer and cause of cancer mortality in males and females (40.2 new cases/100,000/year and 36.5 deaths/100,000/year). Colorectal cancer accounted for 25.1 new cases/100,000/year and 14.7 deaths/100,000/year, and breast cancer for 28.6 new cases/100,000/year and 11.1 deaths/100,000/year. The invasive neoplasms that presented the greatest statistically significant increasing trends during the past 22 years were: lung and bronchus (in women), colorectal cancer (in both sexes), cervical cancer, leukemia (in men) and thyroid cancer (in both sexes).
Although the Cretan cancer rates are still lower than the mean European ones, significant increasing trends were identified; indicating the urgency for clinical and public health measures. Since the cancers that account the most in this increase are preventable by smoking cessation, screening, and vaccination. High priority should be given to the development of population-based interventions.
Clinical trial identification
Legal entity responsible for the study
University of Crete
Region of Crete
All authors have declared no conflicts of interest.