Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

Poster Display

3236 - Cost of care in first line advanced NSCLC patients: Chemotherapy vs targeted therapy


08 Oct 2016


Poster Display


Janna Radtchenko


Annals of Oncology (2016) 27 (6): 416-454. 10.1093/annonc/mdw383


J. Radtchenko1, B. Korytowsky2, K. Tuell3, M. Bhor4, B. Feinberg5

Author affiliations

  • 1 Heor, Cardinal Health, 43017 - Dublin/US
  • 2 Outcomes Research, Bristol-Myers Squibb, Princeton/US
  • 3 Hsor, Bristol-Myers Squibb, Princeton/US
  • 4 Heor, Cardinal Health, Dublin/US
  • 5 Oncology, Cardinal Health, Dublin/US


Abstract 3236


Targeted therapies have increasingly placed drug cost in the spotlight. This represents only one aspect of cancer treatment cost. To provide a comprehensive view, we analyzed first-year drug costs, procedures and acute care interventions for a NSCLC patients on chemo vs TT in the 1L setting.


Using Inovalon's MORE2 Registry® US claims data, aNSCLC pts were identified by International Classification of Diseases-9 codes from July 2013 to June 2014. Inclusion: aNSCLC pts >18 years who received 1L systemic therapy within 6 months (mo) of diagnosis. Exclusion: pts with small-cell lung cancer or secondary malignancies, clinical trial pts, pts with


Of 5319 1L pts, 1070 (20%) had ≥12 mo of follow-up and were included in the analysis. Of those, 23% received TT (242 pts); 62% (659 pts) incurred inpatient costs. Results of the analysis are presented in the table.

All pts (N = 1070) Pts with inpatient costs (N = 659) TT pts (N = 242) Chemo pts (N = 828)
Mean follow-up, mo 20.3 21.3 21.2 20.1
Mean 1L TC, $ 110,138 118,898 150,272 100,624
Mean 1L TC monthly, $ 5,414 5,595 7,086 4,996
Outpatient costs and subcategories
Outpatient costs, % 87 79 92 86
Systemic therapy 27 21 59 19
Supportive care 11 10 2 14
Office visits 2 2 2 2
Labs & diagnostics 2 2 2 2
Radiation/surgery 2 2 1 2
Other drugsa 26 26 18 28
Other procedures 17 16 9 19
Inpatient costs, % 13 21 8 14

aMay not have been related to a NSCLC


The study showed considerable TC in 1L aNSCLC, with systemic therapy representing a significant share. Pts with inpatient care incurred higher TC, and chemo pts had a higher share of inpatient costs vs TT pts. Alternatives to traditional chemo may allow for savings across non-drug-related outpatient and inpatient costs.

Clinical trial identification

Legal entity responsible for the study

Bristol-Myers Squibb


Bristol-Myers Squibb


J. Radtchenko: Participation in funded or unfunded research on a technology, process, or product development or are the principal investigator for a project related to research from Cardinal Health, analyst and study director. B. Korytowsky, K. Tuell: Employment and Stock or Other Ownership from BMS. All other authors have declared no conflicts of interest.

This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings