Selection of Recent Oncology Articles Published in Nature Medicine

13 Mar 2019

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic s u bgroups

Breast Cancer;  Translational Research

22 Aug 2018

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.

Melanoma;  Immunotherapy

15 Aug 2018

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors.

Central Nervous System Malignancies

08 Aug 2018

Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab.

Non-Small Cell Lung Cancer;  Personalised/Precision Medicine

18 Jul 2018

Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib.

Leukaemia

18 Jul 2018

Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer.

Gastric Cancer;  Personalised/Precision Medicine

20 Jun 2018

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer.

Translational Research;  Breast Cancer;  Basic Principles in the Management and Treatment (of cancer)

13 Jun 2018

A transcriptionally and functionally distinct PD-1(+) CD8(+) T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

29 May 2018

Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.

Oesophageal Cancer;  Gastric Cancer;  Translational Research;  Basic Principles in the Management and Treatment (of cancer)

05 May 2018

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.

Leukaemia;  Translational Research;  Basic Principles in the Management and Treatment (of cancer)

02 May 2018

Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.

Lymphomas

02 May 2018

Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial.

Breast Cancer;  Translational Research;  Basic Principles in the Management and Treatment (of cancer)