37P - Domestic cooking fuel as a risk factor for lung cancer in women: A case control study

Date 15 April 2016
Event European Lung Cancer Conference 2016 (ELCC) 2016
Session Poster lunch
Topics Aetiology, epidemiology, screening and prevention
Thoracic malignancies
Basic Scientific Principles
Presenter Asmin Sha
Citation Journal of Thoracic Oncology (2016) 11 (supplement 4): S57-S166. S1556-0864(16)X0004-4
Authors A. Sha
  • Microbiology, PSM DENTAL COLLEGE AND HOSPITAL, 679338 - Thrissur/IN

Abstract

Background

Tobacco smoking is the most common risk factor for lung cancer. But a significant proportion of lung cancer occurs in non-smokers. Indoor pollution due to domestic fuels has been recently implicated as a causative agent in lung cancer especially in women. We conducted a case control study to find out the role of Domestic Cooking Fuel as a risk factor for Lung Cancer in Indian women.

Methods

In the case control study 67 women with proven lung cancer were recruited. Forty-six females having a non-malignant respiratory disease constituted the control group. The patients and controls were asked about the exposure in various cooking fuels using a questionnaire.

Results

There were 50(74.6%) non-smokers and 17(25.4%) smokers among the female cancer cases (p = 0.016). Adenocarcinoma was the commonest histological type of malignancy (n = 26, 38.8%) in the whole group and was the predominant form in the non-smoking females. Tobacco smoking was the most important risk factor for lung cancer with OR of 4.87 (95% CI 1.34–17.76). Among non-smokers out of all the cooking fuels the risk of development of lung cancer was highest for biomass fuel exposure with an odds ratio of 5.33 (95% CI 1.7–16.7). Use of mixed fuels was associated with a lesser risk (OR = 3.04, 95% CI 1.1–8.38).

Conclusions

This study indicated that domestic cooking fuel exposure is an important risk factor in the causation of lung cancer among women in addition of exposure to tobacco smoke.

Clinical trial identification

not applicable

Legal entity responsible for the study

PSM Dental College and Hospital

Funding

PSM Dental College and Hospital

Disclosure

All authors have declared no conflicts of interest.