500PD_PR - Influencing factors on chemotherapy-related cognitive impairment in patients with gastrointestinal cancer

Date 18 December 2016
Event ESMO Asia 2016 Congress
Session Supportive and palliative care
Topics Cytotoxic agents
Oesophageal Cancer
Complications/Toxicities of treatment
Gastrointestinal Cancers
Presenter Jeong Hye Kim
Citation Annals of Oncology (2016) 27 (suppl_9): ix161-ix162. 10.1093/annonc/mdw596
Authors J.H. Kim1, K.S. Choi2
  • 1Department Of Clinical Nursing, University of Ulsan College of Medicine, 05505 - Seoul/KR
  • 2Department Of Nursing, Chung-Ang University, Seoul/KR

Abstract

Background

The purpose of this study was to identify factors that influence Chemotherapy-related Cognitive Impairment in patients with gastrointestinal cancer

Methods

Eighty four gastrointestinal cancer patients receiving or completed chemotherapy within 6 months were recruited in the cross-sectional survey design. The instruments were numeric rating scale-pain, Functional Assessment of Chronic Illness Therapy (FACIT)-Cognitive function, FACIT-Fatigue and Center for Epidemiological Studies Depression (CES-D) Scale.

Results

The level of Chemotherapy-related Cognitive Impairment was 20.89±18.20. Chemotherapy-related Cognitive Impairment was significant correlated with fatigue, and depression. On stepwise regression analysis, the most important factors related to the Chemotherapy-related Cognitive Impairment were mean pain level, fatigue and depression. These variables explained 41.0% of Chemotherapy-related Cognitive Impairment.

Conclusions

The level of Chemotherapy-related Cognitive Impairment was relatively low. However, it is important to apply nursing intervention including assessment of Chemotherapy-related Cognitive Impairment level in cancer patients receiving or completed chemotherapy and to consider pain, fatigue and depression.

Clinical trial indentification

no

Legal entity responsible for the study

N/A

Funding

N/A

Disclosure

All authors have declared no conflicts of interest.