199P - Which is the most common malignancy that profits from the lung metastasectomy? Ten years experience

Date 15 April 2016
Event European Lung Cancer Conference 2016 (ELCC) 2016
Session Poster lunch
Topics Surgery and/or Radiotherapy of Cancer
Presenter Fatmir Caushi
Citation Journal of Thoracic Oncology (2016) 11 (supplement 4): S57-S166. S1556-0864(16)X0004-4
Authors F. Caushi1, D. Xhemalaj2, I. Skenduli1, H. Hafizi1, Z. Pupla1, A. Hatibi1, E. Shima1, E. Selenica1, J. Gjerazi1, B. Gega3
  • 1Thoracic Surgery, University Hospital of Lung Disease "Shefqet Ndroqi", 12345 - Tirana/AL
  • 2Morfology, University Hospital of Lung Disease "Shefqet Ndroqi", 12345 - Tirana/AL
  • 3Radiology, University Hospital of Lung Disease "Shefqet Ndroqi", 12345 - Tirana/AL

Abstract

Background

Lung is often affected by metastases from other organs that are subject of surgery. The efficacy of surgical treatment in pulmonary metastases depends on type of primary tumors and several clinical factors such as: risk of metastasis in other organs, sensitivity to chemotherapy and hormonotherapy and the possibility of a new primary tumor. The aim of our study was to find the most common metastasis in lung, to evaluate the benefits of metastasectomy and the possible prognostic factors associated with overall survival after surgical treatment.

Methods

This is a retrospective, descriptive study from January 2004 to December 2014. Data were examined for age, gender, primary tumor histology, operative approaches and resection margins. The surgical approach used was wedge resection in free margins confirmed also by histopathology. Kaplan–Meier analysis was used to estimate the survival data one year after metastasectomy.

Results

112 pulmonary metastasectomies were performed (males 64, females 48). Median age was 38.2 years. Definitive pathology revealed sarcoma in 54%, epithelial tumor in 36%, and melanoma in 10%. Complete resection (R0) was achieved in all patients. Average postoperative hospital length of stay was 7.4 days. The 1-year survival rates were 64% for epithelial tumors, 43% for sarcomas.

Conclusions

Most common lung metastasis was sarcoma but epithelial tumor profits much more from metastasectomy. Pulmonary metastasectomy is an effective choice of treatment. Univariate analyses verified that histopathology of the tumor, disease-free interval, number of metastatic lesions, and lymph node involvement were significant prognostic factors in patients undergoing pulmonary metastasectomy.

Clinical trial identification

Legal entity responsible for the study

Fatmir Caushi

Funding

Fatmir Caushi

Disclosure

All authors have declared no conflicts of interest.