1602P - Hope Herth Index (HHI): a validation study in Italian patients with solid and haematological malignancies on active oncological therapies

Date 01 October 2012
Event ESMO Congress 2012
Session Poster presentation III
Topics Supportive Care
Haematologic Malignancies
Presenter Carla Ripamonti
Authors C.I. Ripamonti1, L. Buonaccorso2, A. Maruelli3, E. Bandieri4, S. Boldini5, M.A. Pessi5, F. Chiesi6, G. Miccinesi7
  • 1Supportive Care In Cancer Unit, Hematologic And Pediatric Onco-hematologic Department, Fondazione IRCCS, Istituto Nazionale Tumori, 20133 - Milano/IT
  • 2Psychology, AMO Association of Oncological Patients from nine towns and villages in the Northen Area of Modena, 41137 - Mirandola (modena)/IT
  • 3Psychology Unit, LILT and Centre for Oncological Rehabilitation CERION of Florence, 50100 - Firenze/IT
  • 4Oncological Unit, Azienda USL Modena CeVEAS Modena, 41137 - Mirandola Modena/IT
  • 5Supportive Care In Cancer, Fondazione IRCCS, Istituto Nazionale Tumori, 20133 - Milano/IT
  • 6Psychology, University of Florence, 50135 - Florence/IT
  • 7Epidemiology, Cancer Prevention and Research Institute ISPO Florence, 50141 - Florence/IT


Aims and background

Although Hope is a term widely used, the experience of hope in patients with chronic diseases or even life threatening is often disregarded due to the scarcity of assessment tools carefully crafted and validated. The aim of the study was to validate the Hope Herth Index (HHI) questionnaire in the Italian population of patients with solid or haematological cancers during oncological active treatment.


After the translation procedures, the psychometric properties of the Italian version of the Hope Herth Index (HHI) were evaluated in 266 patients with non-advanced cancer cared for in four different settings. Summative scores ranged from 12-48, with a higher score denoting greater hope. Confirmative factorial analysis to assess dimensionality was performed. The test/retest reliability was assessed by means of the Linn concordance coefficient (two weeks interval, 80 patients). Concurrent validity was assessed through the following questionnaires: Hospital Anxiety and Depression Scale (HADS), Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being (FACIT-Sp), Edmonton Symptom Assessment Scale (ESAS) and System Belief Inventory (SBI-15R).


A total of 266 patients were enrolled. Confirmative Factor analysis did not confirm the original three factors solution, whereas a one factor solution did perform well. Cronbach alpha was 0.84. Test-retest reliability was 0.64 (95% C.I.: 0.51; 0.76). Large convergence was found with spiritual well being as measured by the FACIT-Sp (0.69) and with anxiety-depression as measured by the HADS (inverse correlation: -0.51). Physical symptoms and religiousness were only slightly correlated, as expected.


The Italian version of Herth Hope Index (HHI) is a valid and reliable assessment tool, useful to initiate conversation with someone who is troubled but finds it difficult to talk, in cancer patients on active oncological treatment during the non advanced stage of the disease, with either solid and haematological cancers.


All authors have declared no conflicts of interest.