1465P - Sleep difficulties, pain and stress in colorectal cancer female patients

Date 01 October 2012
Event ESMO Congress 2012
Session Poster presentation III
Topics Psychosocial Aspects of Cancer
Colon and Rectal Cancer
Presenter Panagiotis Heras
Authors P. Heras, V. Niarou, E. Andrikopoulos, M. Hera
  • Internal Medicine, General Hospital of Naflio, 113 64 - Athens/GR



This study examined sleep difficulties, pain and stress among women undergoing surgery for colorectal cancer(CC).


Perceived distress was assessed with Perceived Stress Scale (PSS). Sleep quailty was assessed using the Pittsburgh Sleep Quality Index (PSQI). Pain severity and interference were assessed using the Brief Pain Inventory (BPI), while frequency of cancer-associated pain was assessed with a single item from the Functional Assessment of Cancer Therapy-Colorectal Cancer (FACT-CC) scale Participants were assessed immediately prior to surgery and then 4-6 weeks following surgery.


Participants were 68 women who completed at least the PSQI at presurgery, 36 to 85 tears old ( M = 61.12, SD = 9.18). Clinically significant sleep disturbance was evident was evident in 48% of participants prior to surgery, 57% showed clinically significant sleep disturbance was associated with greater stress (p < 0.01), cancer pain frequency (p < 0.01) and pain interference (p < 0.01). Frequency of cancer pain decreased significantly following surgery (p < 0.05); however, there were no changes in sleep disturbance, pain severity/interference, all stress scores from pre to post surgery. Following surgery, greater total sleep disturbance remain associated with: greater stress(p < 0.01) and cancer pain frequency (p < 0.01) but was no longer associated with pain interference.


Sleep disturbance is prevalent among women both prior to and following surgical resection for CC. In addition, associations among sleep disturbance, stress and pain are present shortly following CC diagnosis and persist throughout the perioperative period.


All authors have declared no conflicts of interest.