1381P - Current or former smokers: Who wants to be screened?

Date 09 October 2016
Event ESMO 2016 Congress
Session Poster display
Topics Bioethics, Legal, and Economic Issues
Presenter Sébastien Couraud
Citation Annals of Oncology (2016) 27 (6): 474-482. 10.1093/annonc/mdw387
Authors S. Couraud1, L. Greillier2, X. Pivot3, L. Guibaudet4, J. Blay5, C. Lhomel6, J. Viguier7, J. Morère8, F. Eisinger9, A.B. Cortot10
  • 1Respiratory Diseases And Thoracic Oncology, Centre Hospitalier Lyon Sud, 69495 - Pierre Bénite/FR
  • 2Multidisciplinary Oncology And Therapeutic Innovations, Hopital Nord, Marseille/FR
  • 3Service Oncologie Medicale, CHU Besançon, Hôpital Jean Minjoz, 25030 - Besançon/FR
  • 4Statistics, KantarHealth, Paris/FR
  • 5Medical Oncology, Centre Léon Bérard, 69008 - Lyon/FR
  • 6Oncology/hematology Institutionnal, Roche, Boulogne-Billancourt/FR
  • 7Medical Oncology, CHRU Bretonneau, 37044 - Tours/FR
  • 8Medical Oncology, Hopital Paul Brousse, 94800 - Villejuif/FR
  • 9Cancer Control, Institute Paoli Calmettes, Marseille/FR
  • 10Pneumology And Thoracic Oncology, DRC / CHRU of Lille, Lille/FR

Abstract

Background

Lung cancer screening (LCS) with annual low-dose CT scans reduced specific and overall mortality in a selected population (age 55-74 yrs, current or former [quit  30 pack-years]). Participation is key to successful screening programs. We assessed smokers' intention to take part in a hypothetical LCS program for smokers.

Methods

The EDIFICE French nationwide observational surveys assess behavior related to cancer screening programs. EDIFICE 4 was conducted from June 12 to July 10 2014 by phone interviews of a representative sample of 1602 subjects (age 40-75 yrs) using the quota method. To identify explanatory factors associated with the intention to take part in a LCS program, we performed 2 comprehensive multivariate stepwise logistic regression analyses: (i) in current and (ii) in former cigarette smokers (who quit 

Results

Among those with no personal history of cancer (N = 1463), 263 current and 170 former cigarette smokers were analyzed in the 2 regression models; 36.4% and 26.3% respectively, intended taking part in a LCS program. In current cigarette smokers, the following were explanatory factors of the intention to take part: have been already screened for lung cancer (OR = 2.81; 95% CI [1.37-5.91]; P 

Conclusions

Intending to take part in LCS programs is a complex decision. Explanatory factors differ between current and former smokers but usual eligibility criteria are not significantly explanatory. Among current smokers, intended participation is strongly associated with the intention to quit smoking.

Clinical trial identification

Legal entity responsible for the study

The EDIFICE surveys are funded by Roche

Funding

The EDIFICE surveys are funded by Roche

Disclosure

S. Couraud, L. Greillier, X. Pivot, J.-Y. Blay, J-F. Morère, F. Eisinger, A. B. Cortot: Honorarium fees from Roche. C. Lhomel: Employee of Roche. All other authors have declared no conflicts of interest.