P-003 - Oesophageal cancer incidence in Niger: first results from a population-based cancer registry

Date 04 July 2015
Event WorldGI 2015
Session Posters
Topics Oesophageal Cancer
Aetiology, epidemiology, screening and prevention
Basic Scientific Principles
Presenter H. Hami
Citation Annals of Oncology (2015) 26 (suppl_4): 1-100. 10.1093/annonc/mdv233
Authors H. Hami1, S.M. Garba2, H.M. Zaki2, A. Soulaymani1, H. Nouhou2, A. Quyou1
  • 1Ibn Tofail University, Kenitra/MA
  • 2Abdou Moumouni University, Niamey/NE

Abstract

Introduction

Oesophageal cancer is one of the most serious types of cancer worldwide, owing to its rapid development and fatal prognosis in most cases. In Western Africa, it is the 21st most commonly diagnosed cancer in both men and women and the 18th leading cause of cancer-related death, with an estimated 1 011 new cases of oesophageal cancer and 928 cancer deaths in 2012 (GLOBOCAN 2012). The aim of this study is to estimate the occurrence of oesophageal cancer in Niger, in terms of incidence and describe its epidemiological characteristics.

Methods

This is a descriptive retrospective study of oesophageal cancer cases, reported between 1992 and 2009 to the Niger Cancer Registry, established in 1992, in the Faculty of Health Sciences at the Abdou Moumouni University in Niamey.

Results

During this 18-year period, there were 40 cases diagnosed with oesophageal cancer in Niger (2.3 new cases per 10 million people per year), accounting for 0.6% of all cancers reported during the study period. Nearly 68% of the cases were men with a male-female ratio of 2.1. The average age at diagnosis of oesophageal cancer was 49.1 ± 11.9 years (range 20-75 years). More than two-thirds (70%) of people diagnosed with the disease were aged 45 years or older, with 62.5% of new cancer cases occurring among those aged 45-64 years. Djerma-Sonrai was more likely to develop oesophageal cancer than any other ethnic groups. The most common histological type was squamous cell carcinoma. Among the cases for which the outcome was known, 7 (17.5%) died within the first year of diagnosis, accounting for 0.8% of all cancer deaths.

Conclusion

Preventing the occurrence of oesophageal cancer is difficult by the fact that the two major histological types, squamous cell carcinoma and adenocarcinoma, differ substantially in their patterns of incidence and key etiologic factors.