577P - Nicotine dependence assessment using Fagerstrom test and Nicotine Replacement therapy (NRT) recommendation techniques for smoking cessation among P...

Date 18 December 2016
Event ESMO Asia 2016 Congress
Session Poster lunch
Topics Aetiology, epidemiology, screening and prevention
Presenter Heeda Rozario
Citation Annals of Oncology (2016) 27 (suppl_9): ix184-ix189. 10.1093/annonc/mdw603
Authors H.P. Rozario
  • Dentistry, DM wayanad institute of Medical Science, 673602 - Calicut/IN



Tobacco is a highly addictive substance. It is estimated that 1.9 billion people currently smoke worldwide. Tobacco kills one in two users. It is responsible for the death of 1 in 10 adults, with 4.9 million deaths occurring worldwide each year. Tribes are a special population with high prevalence of smoking. Most people who try to stop smoking do so unassisted, and many return to smoking within a few months. There is now substantial evidence that pharmacotherapy, such as nicotine replacement therapy (NRT), can significantly increase an individual’s chances of stopping. Indeed, it is widely recommended that pharmacotherapy be incorporated into any quit attempt when not contraindicated.


Objectives: To investigate the effectiveness of nicotine replacement therapy (NRT) for smoking cessation among Paniya tribes. Design: Randomised controlled trial. Participants and setting: 200 Paniya tribal smokers from South India, aged 18 years and older with a Fagerstrom score of 1 and above were included in the study. Interventions: The scoring of the tribal patients was done using Fagerstrom test for nicotine dependence. The NRT recommendation chart was used to give the appropriate intervention according to the scoring criteria. Main outcome measures: Self-reported abstinence assessed by questionnaires at 1, 2, 3 and 6 months.


Of the 200 patients approached, 165 (82.5%) agreed to participate; five of these were later excluded. Among the 160 tried NRT during the study period. At 30-day follow-up, 82 (51.25%) who had used NRT planned to continue using them, it reduced to 74,52 and 30 at the end of 2, 3 and 6 months respectively. Average cigarette consumption decreased from 15.6 per person/d to 7.6 over the study period (P < .001).


Pre existing traditions and customs, superadded with illiteracy in Paniya tribes have resulted in reduction in the success rate of NRT therapy. However the therapy have paved the way in reduction of daily tobacco use.

Clinical trial indentification


Legal entity responsible for the study





All authors have declared no conflicts of interest.