Translational Research

• Expert video report on Targeting NTRK gene fusions across cancers
• Understanding the biology of TNBC: Where are we in 2019?
• miRNA expression profiles in BRCA1-associated breast cancers reveal upregulation of specific miRNAs in tumors lacking a clear second hit in a large...
• The mutational profile of IBC reveals higher mutational burden, deficiency of homologous recombination and NOTCH signalling
• Para-necrotic expression of VEGFA metagene signature identified by single-cell profiling
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• What is different in the biology of Inflammatory Breast Cancer?
• Outcome and mutational landscape of patients with PIK3CA-mutated metastatic breast cancer (mBC)
• Hereditary breast cancer and PARP inhibitors
• Immune cell dynamics induced by a single dose of pembrolizumab as revealed by single-cell RNA profiling
• Immune functions of follicular helper CD4+CXCR5+ T cells in human breast cancer
• Clinical significance of BCL-2 with basal and non-basal triple negative breast cancer (TNBC)
• Investigation on the MyD88 mediated TLR3 signaling via cell surface in breast cancer
• Association of serum IGF1 and adiponectin in prognosis of breast cancer metastasis
• Regulation of MMP9 expression by human arylamine N-acetyltransferase (NAT1) via Hif-1a
• CD146 suppresses breast tumor via its novel downstream signaling pathway, Latexin/Akt/NFκB
• Sensitivity and dynamic range of CellSearch based CSF DTC enumeration in patients with breast cancer related leptomeningeal metastases (LM)
• Heterozygous mutation in fanconi anemia genes associated with hereditary breast cancer
• Germline PALB2 heterozygous mutations in breast cancers: Haploinsufficiency paradigm
• RNA signatures from tumor-educated platelets (TEP) enable detection of early-stage breast cancer
• Defining the physiological miRNA landscape in nipple aspirate fluid
• WNT, Hedgehog and NOTCH signaling pathways in triple negative breast cancer with high and low content of cancer stem cells
• Prognostic significance of BCL-2 expression in triple negative breast cancer (TNBC)
• The early changes of ΔSUV is a predictive marker of response and outcome in everolimus treated patients with mBC

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