262P - MRI and MDCT for the diagnosis of pancreatoduodenal zone tumors

Date 17 December 2016
Event ESMO Asia 2016 Congress
Session Poster lunch
Topics Pancreatic Cancer
Staging procedures (clinical staging)
Presenter Oktyabr Teshaev
Citation Annals of Oncology (2016) 27 (suppl_9): ix68-ix85. 10.1093/annonc/mdw582
Authors O.R. Teshaev1, M.K. Khodjibekov2, G.E. Rakhmonova2
  • 1General Surgery For Gp, Tashkent Medical Academy, 100100 - Tashkent/UZ
  • 2Oncology And Radiology, Tashkent Medical Academy, 100100 - Tashkent/UZ

Abstract

Background

Entering of the MRCP (magnetic resonance cholangiopancreatography) and MDCT (multidetector computed tomography) methods in medical oncology increased chance of diagnosing and monitoring of treatment of the tumors of pancreatoduodenal area as the other organ pathologic conditions and tumors. Almost all pancreatoduodenal area tumors give same symptoms and same clinical future, MRCP and MDCT can concretize results of traditional methods such as ultrasonography and cholangiography. And also gives chance to choose right treatment plan.

Methods

MRCP with pathologic correlation was provided for 92 patients, 19-85 year sold, with complication of biliousness, nausea, poor appetite and itching sensation of skin in radiology department of Tashkent medical academy and department of radiology of the Research Center of Oncology of the Uzbekistan.

Results

MRCP shows stable biliary hypertension with different etiologies: they are 43.5% head of pancreas, 30% tumor of portal area, 12% tumors of distal common bile duct, 8% tumors was from papilla of duodenum, 4.5% after metastasis, 2% due to liver tumors. Tumor size varied with its location and origin of tumor. Main sings by MRCP was dilated hepatic bile ducts untill 23 mm with irregular border and wall thickness. Mostly stable changes were founded in right side of biliary tree, with obvious deformation of biliary tree. In one case changing of biliary tree with visible clinical evidence such as biliousness was in young lady after trauma MRCP shoved stricture due to conjunctive tissue. In all patients local lymph nodes was enlarged until 0.8-1.2 cm. 5 patients tumors of pancreas origin was antral area tumors. Infiltration of stomach wall diameter was 14-23 mm. 4 patients tumor spreads till bifurcation of common hepatic bile duct, with large intrahepatic bile ducts with 16 mm, wall of these ducts was linear like (weak), walls between bile duct and portal vein was poor due to inflammation. Signal intensity was very low on these areas.

Conclusions

MRCP gives chance to detect changing in biliary system, liver tissue and other adjacent structures. Shows growing rate of tumor, location, and structure of it.

Clinical trial indentification

In the Section of Gastrointestinal noncolorectal cancer diagnostics.

Legal entity responsible for the study

Rakhmonova Gulbahor

Funding

Tashkent medical academy

Disclosure

All authors have declared no conflicts of interest.