TRK Inhibitors

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Several TRK inhibitors are in clinical development or have been licensed in some countries. These agents differ in stage of development, characteristics, and mode of action, as well as whether they address acquired resistance to TRK protein inhibition. 

Click on the links below to find out more about acquired resistance to TRK protein inhibition, as well as first-generation and next-generation TRK inhibitors that are either licensed or under development.