NTRK Gene Fusions as Oncogenic Drivers

Previous Page   Next Page


NTRK gene fusions are oncogenic drivers and the resultant TRK fusion protein is a treatment target across many tumour types. The following section describes the various mechanisms of TRK activation in cancer, what NTRK gene fusions are, including how they are formed and their resulting activity, and the epidemiology of NTRK gene fusions.