SIRT in Metastatic Colorectal Cancer: The Focus on SIRFLOX Study Results

Speaker: Dirk Arnold

D. Arnold describes different treatment scenarios available for patients with colorectal cancer (CRC) and liver metastases and subsequently focuses on selective internal radiotherapy (SIRT), in particular SIR-Spheres Y-90 resin microspheres. Furthermore, he elaborates the results from the SIRFLOX trial in first-line treatment of non-resectable CRC liver metastases.

Discussion Points

  • How liver metastases from colorectal cancer could be managed?
  • What is a principle of action of selective internal radiotherapy using SIR-Spheres Y-90 resin microspheres?
  • Results from the SIRFLOX study with yttrium-90 resin microspheres plus (B)FOLFOX versus (B)FOLFOX alone as first-line treatment of non-resectable liver metastases from colorectal cancer.