BRAF Mutant Colorectal Cancer: Current Scenario and Future Perspectives

Speaker: Loredana Vecchione

L. Vecchione summarises recent results in the treatment of RAS-, BRAF-mutant and wild-type colorectal cancer (TRIBE trial), confirming the peculiarity of BRAF-mutant CRC. New research is being conducted to identify specific genes related to the BRAF mutation to be possibly targeted with new agents.

Discussion Points

  • Topline findings in BRAF mutant subgroups in recent colorectal cancer trials
  • Recommendations for practice: What to do in BRAF mutant colorectal patients?
  • What are key considerations for characterising BRAF mutant colorectal cancer as a different entity?