Risk assessment for gastrointestinal cancers in patients with family history of gastrointestinal cancer: Multi-center interim analysis study in the...

Date 29 June 2016
Event ESMO World Congress on Gastrointestinal Cancer 2016
Session ESMO World Congress on Gastrointestinal Cancer 2016 - Abstracts book
Presenter J.W. Chung
Citation Annals of Oncology (2016) 27 (2): 102-117. 10.1093/annonc/mdw200
Authors J.W. Chung1, Y.J. Lim2, S.M. Kim3, J. Lee4, J.-. Han5, Y.S. Kim6, D.-. Myung7, D.K. Jang8, S.P. Hong9
  • 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Medical Center, Jung-gu, Republic of Korea, /
  • 2Division of Gastroenterology, Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University, College of Medicine, Goyang, Republic of Korea, /
  • 3Division of Gastroenterology and Hepatology, Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Republic of Korea, /
  • 4Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical School, Chosun University, Gwangju, Republic of Korea, /
  • 5Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Republic of Korea, /
  • 6Division of Gastroenterology, Department of Internal Medicine, Digestive Disease Research Institute, Wonkwang University Sanbon Hospital, Gunpo, Republic of Korea, /
  • 7Division of Gastroenterology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea, /
  • 8Seoul National University College of Medicine, Seoul, Republic of Korea, /
  • 9Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea, /

Abstract

A number of personal and environmental risk factors are known to gastrointestinal (GI) cancer development. Cancer syndromes are also responsible for increased incidence of same or different cancers in involved family members. However, only a few genetic abnormalities were known to cancer syndrome. We wonder whether family history of GI cancers in first relatives has relevance to an increased risk of any GI cancer or not. But there were few studies investigating the risk of family history of GI cancers for other GI cancers. The aim of this study was to evaluate the relationship between family history of GI cancers and incidence of any GI cancer in Korean populations.