Macrophage coculture enhanced invasion of gastric cancer cells via FOXQ1 pathway

Date 29 June 2016
Event ESMO World Congress on Gastrointestinal Cancer 2016
Session ESMO World Congress on Gastrointestinal Cancer 2016 - Abstracts book
Presenter J. Zhang
Citation Annals of Oncology (2016) 27 (2): 1-85. 10.1093/annonc/mdw199
Authors J. Zhang1, J. Zhang2, Y. Yan3, J. Wang4
  • 1The Second Department of Thoracic Surgery, First Affiliated Hospital, Medical School, Xi'an Jiaotong University, Xi'an, China, /
  • 2First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China, /
  • 3First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China, /
  • 4Department of Thoracic Oncosurgery, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, China, /

Abstract

Tumor-associated macrophages (TAMs) promoted the invasion of gastric cancer cells, but the exactly mechanism has not been clarified. FOXQ1 is a prognostic marker for patients with gastric cancer. However, the role of FOXQ1 signaling between TAMs and gastric cancer remains unclear.