Impact of chromogranin A, grade, and mitotic rate in small, non-functional pancreatic neuroendocrine tumors: q US population based study

Date 29 June 2016
Event ESMO World Congress on Gastrointestinal Cancer 2016
Session ESMO World Congress on Gastrointestinal Cancer 2016 - Abstracts book
Presenter K. Mirkin
Citation Annals of Oncology (2016) 27 (2): 118-128. 10.1093/annonc/mdw198
Authors K. Mirkin1, C. Hollenbeak2, J. Wong2
  • 1Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA, /
  • 2Penn State Hershey Medical Center, Hershey, Pennsylvania, USA, /


Small (≤2cm) pancreatic neuroendocrine tumors (PNETs) are a unique subset of pancreatic neoplasms. Chromogranin A levels (CgA), mitotic rate, and histologic grade are often used to characterize PNET behavior, but debate continues around long-term clinical outcomes in small tumors. This study evaluates the survival impact of these factors in a US population.