Correlation of Mitotic Index and Ki-67 and Their Impacts on Survival of Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) at Ramathibodi Hosp...

Date 29 June 2016
Event ESMO World Congress on Gastrointestinal Cancer 2016
Session ESMO World Congress on Gastrointestinal Cancer 2016 - Abstracts book
Presenter T. Dejthevaporn
Citation Annals of Oncology (2016) 27 (2): 1-85. 10.1093/annonc/mdw199
Authors T. Dejthevaporn1, V. Jennetisin2, S. Rattanasiri3, P. Sornmayura4
  • 1Mahidol University, Ramathibodi Hospital, Rajthevi, Thailand, /
  • 2Phyathai 1 Hospital, Phayathai, Thailand, /
  • 3Mahidol, University, Ramathibodi Hospital, Rachatevi, Thailand, /
  • 4Department of Pathology, Ramathibodi Hospital, Rajthevi, Thailand, /

Abstract

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are the most prevalent type of neuroendocrine tumors. Limited data is available on GEP-NET in Thai patients. Proliferative index as determined by mitotic rate/index (MI) and Ki-67 labelling index have proven to be strong prognostic factors in GEP-NETs and many experts have recommended that both markers be performed in all cases although this is not accepted universally. Ki-67 is not widely available and/or standardized in Thailand. Therefore, this study aimed to explore the agreement of these 2 methods and their correlation with survival in our center.