An Evaluation Based on a Systematic Review of Epidemiologic Evidence of Colorectal Cancer Risk among the Alcohol Consuming Indian Population

Date 29 June 2016
Event ESMO World Congress on Gastrointestinal Cancer 2016
Session ESMO World Congress on Gastrointestinal Cancer 2016 - Abstracts book
Presenter A. Mishra
Citation Annals of Oncology (2016) 27 (2): 1-85. 10.1093/annonc/mdw199
Authors A. Mishra1, S. Mishra2
  • 1Gandhi Medical College, Bhopal, India, /
  • 2Pharmacy, Bhopal, India, /

Abstract

The number of colorectal related deaths is estimated to be approximately 608000 worldwide, accounting for 8% of all cancer deaths and making Colorectal cancers the fourth most common cause of death due to cancer. In India, the annual incidence rates for colon cancer and rectal cancer are 4.4 and 4.1 per lakh respectively. As we know alcohol drinking may be associated with incidence of colorectal cancer. On the basis of a systematic review of epidemiological evidence, we evaluated this association among the Indian population. Although numerous studies reported a positive association between alcohol drinking and colorectal cancer risk, it remains unclear whether alcohol drinking is causally related to carcinogenesis of the colorectum. A report from the World Cancer Research Fund and American Institute for Cancer Research concluded that alcohol drinking ‘probably’ increases colorectal cancer risk, whereas a recent report of a Joint World Health Organization (WHO)/Food and Agriculture Organization (FAO) Expert Consultation did not include colorectal cancer in the list of alcohol-related malignancies.