A study on response for irreversible electroporation of colon cancer cell using multiphoton microscopy

Date 29 June 2016
Event ESMO World Congress on Gastrointestinal Cancer 2016
Session ESMO World Congress on Gastrointestinal Cancer 2016 - Abstracts book
Presenter B. Keum
Citation Annals of Oncology (2016) 27 (2): 1-85. 10.1093/annonc/mdw199
Authors B. Keum1, I.K. Yoo1, J.M. Lee1, S.H. Kim1, H.S. Choi2, E.S. Kim3, Y.T. Jeen4, H.J. Chun3, C.D. Kim1
  • 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea, /
  • 2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Institute of Gastrointestinal Medical Instrument Research, Korea University College of Medicine, Seoul, Republic of Korea, /
  • 3Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea, /
  • 4Division of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul, Republic of Korea, /

Abstract

Irreversible electroporation (IRE) is a promising novel technique for the ablation of tumors using energy current pulses to induce cell death. IRE has been shown to be an effective method of removing undesired cells without thermally destructing the surrounding tissues. To provide a reliable and rapid process of IRE ablation in colon cancer, we have developed multiphoton (MP) probes for DNA (ABI-Nu), and mitochondria (PMT).