The workload and impact of a dedicated cancer of unknown primary (CUP) service on patients with imaging suggestive of metastatic disease

Date 28 June 2017
Event ESMO World Congress on Gastrointestinal Cancer 2017
Session ESMO World Congress on Gastrointestinal Cancer 2017
Topics Carcinoma of Unknown Primary Site (CUP)
Presenter Danny Ulahannan
Citation Annals of Oncology (2017) 28 (suppl_3): iii13-iii136. 10.1093/annonc/mdx261
Authors D. Ulahannan, E. Keen, G. Stewart, J. Bell, K. Planche, N. Power, S. Navalkissoor, R. Craig, T. Luong, J. Watkins, I. Clark, R. Gillmore
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In response to NICE guidelines (2010) “Diagnosis and Management of Metastatic Disease of Unknown Primary Origin (MUO)” the Royal Free Hospital (RFH), London established a multidisciplinary service whose role is to review all patients with suspected metastatic disease on the basis of basic abnormal imaging. The aims of this service are to: streamline and organise appropriate investigations with early consultant-led oncology input; provide access to psychological support and information from a dedicated clinical nurse specialist (CNS); expedite time to diagnosis and treatment and facilitate earlier input from palliative care.


From 1st April 2013- 31st March 2016 the RFH CUP service received 455 referrals. We report a retrospective analysis of objective measures and outcomes of one of the largest CUP services in the United Kingdom.