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Poster display session

159P - The relation between obesity and cancer of gastrointestinal tract in Korea: The data from Statistic Korea between 2001 and 2016

Date

23 Nov 2019

Session

Poster display session

Topics

Tumour Site

Gastric Cancer

Presenters

Hee Man Kim

Citation

Annals of Oncology (2019) 30 (suppl_9): ix42-ix67. 10.1093/annonc/mdz422

Authors

H.M. Kim1, J.S. Choi2

Author affiliations

  • 1 Internal Medicine, Yonsei University Wonju College of Medicine, 264261 - Wonju/KR
  • 2 Internal Medicine, Catholic Kwandong University, Incheon/KR

Resources

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Abstract 159P

Background

Obesity is a risk factor for several cancer. In Korea, prevalence of obesity has increased and incidence of several cancers of gastrointestinal (GI) tract, such as colon cancer and rectal cancer have increased. The aim of this study was to evaluate the association between obesity prevalence and cancer incidence of gastrointestinal tract in Korea adults.

Methods

The data were collected from the webpage of Statistic Korea, where the incidence of GI tract cancer between 2001 and 2016 was obtained from National Cancer Center, and the prevalence of obesity between 2001 and 2016 was obtained from National Health and Nutrition Examination Survey. The obesity was defined as BMI ≥25 kg/m2 among adults ≥30 years old. The association between obesity and cancer of GI tract was calculated by using linear regression analysis.

Results

In men, prevalence of obesity was significantly associated with esophageal cancer (β: 0.176, P = 0.001), colon cancer (β: 2.034, P = 0.013), rectal cancer (β: 1.305, P = 0.035), gallbladder cancer and other biliary tract cancer (β: 0.712, P < 0.0001), and pancreatic cancer (β: 0.717, P < 0.0001). But, gastric cancer (β: 1.396, P = 0.076) and liver cancer (β: 0.122, P = 0.496) were not associated with obesity prevalence (Table) In women, incidence of GI tract cancer was not associated with obesity prevalence.Table:

159P Linear regression between obesity and GI cancer in men adults

CancerBeta coefficient95% CIP value
Esophageal cancer0.1670.092 - 0.2410.001
Gastric cancer1.396-1.76 - 2.9680.076
Colon cancer2.0340.535 - 3.5330.013
Rectal cancer1.3050.114 - 2.4950.035
Liver cancer0.122-0.262 - 0.5060.496
Gallbladder and other biliary tract cancer0.7120.498 - 0.927<0.0001
Pancreatic cancer0.7170.434 - 0.999<0.0001

Conclusions

In Korean adults, incidence of some GI tract cancer seems to be associated with obesity prevalence.

Clinical trial identification

Editorial acknowledgement

Legal entity responsible for the study

The authors.

Funding

Has not received any funding.

Disclosure

All authors have declared no conflicts of interest.

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