Malignant Melanoma of the Palate: Report of a Metastatic Case

Date 24 November 2018
Event ESMO Asia 2018 Congress
Session Poster display - Cocktail
Topics Melanoma
Presenter Mel Valerie Cruz-Ordinario
Authors M.V.B. Cruz-Ordinario1, C.A.D.G. Boado2, A.E. Gorospe1
  • 1Medical Oncology, St. Luke's Medical Center – Quezon City, 1102 - Quezon City/PH
  • 2Medicine, St. Luke's Medical Center – Quezon City, 1102 - Quezon City/PH


Case Summary

Primary malignant melanoma of the oral cavity is a rare malignancy with an incidence of 0.2 to 8% of all melanomas. Melanoma arises from the malignant transformation of the melanocyte and cutaneous melanomas are the most common followed by ocular, mucosal and melanoma of unknown primary site. Here we present a case of a 54 year old male who presented with a pigmented lesion on the palate, a type of mucosal melanoma. Due to the rarity of this disease, it is infrequently studied. Hence, epidemiology, etiology, pathogenesis and prognosis still remain less understood than cutaneous melanoma. Early diagnosis is warranted as therapeutic options are limited for advanced and metastatic disease. Surgery is the primary therapeutic management and complete resection is the main goal. If not feasible, radiotherapy may also be employed to achieve local control and enhance locoregional response. Prognosis is generally poor for metastatic disease and there are no guidelines yet on the use of systemic therapy.

Editorial acknowledgement


We are indebted to the Institutes of Pathology, Radiology and Nuclear Medicine for the images shown in this report.

Clinical trial identification