Epidemiology of AYA(adolescents and young adults) cancer in National Institute of Cancer Research and Hospital(NICRH),Dhaka, Bangladesh.

Date 24 November 2018
Event ESMO Asia 2018 Congress
Session Poster display - Cocktail
Topics Cancers in Adolescents and Young Adults (AYA)
Presenter Abdullah Al Mamun Khan
Citation Annals of Oncology (2018) 29 (suppl_9): ix129-ix138. 10.1093/annonc/mdy444
Authors A.A.M. Khan1, P.S. Akthar2
  • 1Medical Oncology, National Institute of Cancer Research & Hospital, 1212 - Dhaka/BD
  • 2Medical Oncology, National Institute of Cancer Research & Hospital, dhaka - Dhaka/BD



Cancers in AYA are increasing but there are few clinical and epidemiological data from developing countries. There are 44.2% people in this 15-39-year age group in Bangladesh. They are in vital age group for their own development, for their country and for the world.


The study was an observational study. Histologically confirmed cancer patients aged 15-39 years registered in NICRH from Jan.2017 to Dec.2017 were included. The patients were grouped according to Birch classification of AYA cancer. Each patient was interviewed and clinical information and demographic profiles were recorded.


Total 581 patients were enrolled, of these, male (M) 315 (54.22%), female (F) 266(45.78%) and M:F=1.18:1. Older AYA patients (35-39 years) were most common,184 (31.65%) followed by younger AYA (15-19 years),129 (22.20%). The remaining 20-24 years, 25-29 years and 30-34 years groups were 58 (9.98%), 91 (15.70%) and 119 (20.47%), respectively. The most common cancers were breast cancer 95 (16.34%) followed by gastrointestinal carcinoma, GCT (Germ Cell Tumor) and GTT (Gestational Trophoblastic Tumor) 70 (12.04%), osseous and chondromatous neoplasms 67 (11.52%), lymphomas 63 (10.84%), soft tissue sarcoma 58 (9.98%) and leukemias 50 (12.50%). The most common cancers in younger AYA (15-19 years) were osseous and chondromatous neoplasms 38 (6.54%) in contrast, older AYA (35-39 years) suffered mainly from breast cancer 45 (7.74%). The leading cancers in the 20-24 year aged group were GCT and GTT 14 (2.41%) and 30-34 years aged group were breast cancer 31 (5.33%). The leading clinical features were swelling 298 (51.26%), pain 138 (23.74%) and fever 110 (18.92%. The majority 224 (38.53%) were educated up to primary level, 76.54% (445) of patients belong to low socioeconomic status groups, 38% (221) were housewives and 70.35% (409) was dependent upon others, 63.98% were rural dwellers, 79.46% (462) patients presented with advanced disease, and 6.88% (40) of patients presented with comorbiditiess. The majority 165 (28.38%) of patients delayed for six months to one year before consulting a registered graduate doctor for proper treatment.


The majority of AYA patients presented at late stage with multiple symptoms as they ignore the symptoms and their economical dependency made the disease more difficult to cure by proper treatment.

Editorial acknowledgement

Clinical trial identification

Legal entity responsible for the study

Dr. Abdullah Al Mamun Khan.


Has not received any funding.


All authors have declared no conflicts of interest.