255P - Complex treatment of patients with mechanical jaundice of tumor etiology (255P)

Date 18 November 2017
Event ESMO Asia 2017 Congress
Session Poster lunch
Topics Hepatobiliary Cancers
Palliative Care
Gastrointestinal Cancers
Presenter Saidrakhim Lukmonov
Citation Annals of Oncology (2017) 28 (suppl_10): x57-x76. 10.1093/annonc/mdx660
Authors S.N. Lukmonov
  • Oncology And Radiology, Tashkent Medical Academy, 100100 - Tashkent/UZ



Complex application of modern minimally invasive techniques in patients with mechanical jaundice (MJ) of tumor etiology.


For the period from 2008 to 2016 177 patients were observed: 55 with metastatic liver cancer (with localization in the portal fissure), 98 with pancreatic head cancer, 7 with tumor lesions of the large duodenal papilla, and 17 with bile duct cancer of complicated with MJ. All patients on admission to the hospital at the first stage there was performed ultrasound investigation of the abdominal cavity, spiral computed tomography (CT) of the hepatopancreoduodenal complex with determination of the block level and subsequent drainage of the liver ducts under ultrasonographic guidance.


In 55 patients with localization of metastatic tumors in the portal fissure complicated by the MJ, the external, external-internal drainage of the intrahepatic ducts was performed at the first stage. Cook sets 8.5-10.2Fr with catheterization of the hepatic ducts were used according to the method of Seldinger. In 98 cases in the presence of pancreatic head cancer, complicated with MJ, 24 percutaneous-transhepatic (HCH) cholecystostomy and 74 HF drainage of the hepatic ducts were performed. At the first stage of development of minimally invasive technologies, preference was given to the formation of HH by the cholecystostomy under ultrasonographic control. For the period from 2008 to 2010, 15 cholecystostomies were performed, from 2011 to 2013. - 5, from 2014 to 2016 years - 4. For the period from 2008 to 2010, 7 drains of the ducts were performed, from 2011 to 2013. - 26, from 2014 to 2016. - 41. In 37 cases on 7-8 days after drainage, the cholecystoenteroanastomosis was applied. In 14 cases, when the drainage was found in the common hepatic or bile duct, the catheter was not removed during the operation. In the near postoperative period, 15 patients died from acute liver-kidney failure, two from acute myocardial infarction.


The use of a complex approach in the surgical treatment of malignant hepatoduodenal complex formations complicated with MJ is a low-traumatic and highly effective method that contributes to reducing the incidence of complications, lethality, as well as improving the results of treatment of oncological patients with MJ.

Clinical trial identification

Legal entity responsible for the study

Tashkent Medical Academy




The author has declared no conflicts of interest.