387P - Clinicopathological Characteristics and Prognostic Factors of Malignant Melanoma: A Retrospective Analysis of a 12-Year Study (387P)

Date 18 November 2017
Event ESMO Asia 2017 Congress
Session Poster lunch
Topics Aetiology, epidemiology, screening and prevention
Skin cancers
Melanoma
Basic Scientific Principles
Presenter Chawalit Chayangsu
Citation Annals of Oncology (2017) 28 (suppl_10): x113-x116. 10.1093/annonc/mdx667
Authors C. Chayangsu
  • Internal Medicine, Surin Hospital, 32000 - Surin/TH

Abstract

Background

Malignant melanoma is the most lethal skin cancer. Unfortunately, we have limited number of studies in Thailand. This study aims to present clinicopathological characteristics and to define possible prognostic factors of malignant melanoma in Thai patients.

Methods

A retrospective study of malignant melanoma in Thai patients in Surin Hospital between 1st January 2005 and 31st December 2016 was conducted. All out-patient and in-patient medical records were reviewed for demographic data and histopathological features. Univariate, multivariate and Kaplan-Meier analysis were used for prognostic factors and overall survival.

Results

Fifty-one patients with confirmed malignant melanoma were identified with 30 males (59%) and 21 females (41%). The mean age was 65.4 years. Duration of time between clinical onset and diagnosis was 13.5 months. Lower extremities and head-neck area were the most common sites 80.4% and 9.8%, respectively. Acral lentiginous melanoma (ALM) was the most common cutaneous type (51.6%). The majority of patients were clinical stage III (50%). Patients with advanced disease had less median survival time 1.7 month compared with localized disease 29.6 months (p 

Conclusions

Malignant melanoma in Thai patients, most were ALM subtype, occured at lower extremities and presented with clinical stage III. The prognosis depends on clinical staging and histologic subtype.

Clinical trial identification

Legal entity responsible for the study

individual person.

Funding

None

Disclosure

All authors have declared no conflicts of interest.