374P - Trends in incidence of head and neck cancers in India

Date 17 December 2016
Event ESMO Asia 2016 Congress
Session Poster lunch
Topics Aetiology, Epidemiology, Screening and Prevention
Head and Neck Cancers
Presenter Clement Joy Kingsly Francis
Citation Annals of Oncology (2016) 27 (suppl_9): ix112-ix122. 10.1093/annonc/mdw587
Authors C.J.K. Francis
  • Social Work, Nestle India Limited, 120012 - Gurgaon/IN

Abstract

Background

India is classified as a lower-middle-income group country by the World Bank. Head and neck cancers are among the 10 most common cancers globallyand are the most common cancers in developing countries, especially in Southeast Asia. In India, it accounts for one fourth of male cancers and one tenth of female cancers. This is mainly attributed to tobacco, areca nut, alcohol, etc. Oral cancers are most common amongst all head and neck squamous cell cancers (HNSCC). HNSCC in the developing world differ from those in the Western world in terms of age, site of disease, etiology, and molecular biology. Poverty, illiteracy, advanced stage at presentation, lack of access to health care, and poor treatment infrastructure pose a major challenge in management of these cancers. The Cancer Atlas project by the Indian Council for Medical Research (ICMR) has shown the incidences of various cancers in different parts of India. Ninety percent of the oral cancer patients in rural areas belong to the lower or lower-middle socio-economic class, and 3.6% are below the poverty line.

Methods

Objectives 1. To determine the trends in incidence of head and neck squamous cell carcinoma over a time period in India. 2. To compare change in the trends of head and neck squamous cell carcinoma of India and developed countries. Materials & Methods The tumor registry data was taken from South Indian cancer registry (Chennai-1986-98) and from a rural (Kancheepuram - 1988-98) registry, which has data for a long period since 1982 and 1987 respectively to identify the change in trends of head and neck cancers. Chennai, a South Indian urban cancer registry caters to an area of 170sq.km and a population of 4.2 millions. The National Cancer Registry Programme of the Indian Council of Medical Research(ICMR) monitors these cancer registry data. The data from these two registries were usedtoanalyze change in trends within the country.

Results

Incidence rate is higher in more developed countries than less developed countries. Male preponderance is forthcoming. .The overall male: female ratio of head and neck cancers in urban population is 2:1and inrural population is 5:1.

Conclusions

A trend is emerging showing that the type of oral cancers that patients present with arechanging, with a definite increase in the number of patients presenting with tonguecancer.

Clinical trial indentification

Legal entity responsible for the study

N/A

Funding

N/A

Disclosure

All authors have declared no conflicts of interest.