25P - Review of reproductive risk factors in breast cancer patients in Toungoo General Hospital, Myanmar

Date 17 December 2016
Event ESMO Asia 2016 Congress
Session Poster lunch
Topics Breast Cancer
Presenter Khin Khin Nwe
Citation Annals of Oncology (2016) 27 (suppl_9): ix1-ix8. 10.1093/annonc/mdw573
Authors K.K.K. Nwe1, S. Aung2, S. Mon3, T.T. Aye3
  • 1Medical Oncology Unit, Taungoo General Hospital, 70201 - Taungoo/MM
  • 2Medical Oncology Unit, Yangon General Hospital, 11131 - Yangon/MM
  • 3Medical Oncology Unit, Bahosi Medical Centre Bahosi Housing Complex, 11131 - Yangon/MM

Abstract

Background

Breast cancer is the most common cancer in Myanmar women. International studies proved that reproductive factors such as nulliparity and older age at first full-term pregnancy increase the risk of developing breast cancer. Breastfeeding can lower breast cancer risk, especially if a woman breastfeeds for longer than one year. We studied the reproductive risk factors of breast cancer patients in Toungoo district, which is situated in lower central part of Myanmar with various races and ethnicities.

Methods

A cross-sectional, hospital based study was carried out in medical oncology unit, 200 bedded Toungoo General Hospital from January 2012 to July, 2016.

Results

Among (210) breast cancer patients registered, only one male patient was noticed. In (209) female patients, age range from 28-91 yrs (median 52.47 yrs). Invasive duct carcinoma 208 [99.52%] and one invasive lobular [0.47%] were found. The most common stages were II B 60 [28.7%] and III A 53 [25%] in this study. Patients with first full-term pregnancy at later age (after 30yrs) were 35 [16.75%]. Among 141 mothers, 140 [99.29%] did breast feeding to their children more than one year duration.rn

Table: 25P Parity and breast cancer patients

rnrnrnrnrnrn rn rn rn rnrnrnrn
Parity Single/P0 P1 P2-4 ≥P5
Patients [%]68 [32.53%]11 [5.26%]95 [45.45%]35 [16.75%]
rn

Conclusions

In this study, it was found that almost all parous women with breast cancer did breastfed their babies in longer duration more than one year. A few patients had first full-term pregnancy after 30year of age and a large number of patients were parity two and more. These data highlights that the breast cancer risk factors in Myanmar women have slight variation from international findings. Further studies with larger sample size with control group should be conducted to find out associated breast cancer risk factors in Myanmar women.

Clinical trial indentification

no trial protocol number

Legal entity responsible for the study

Medical Oncology Unit, Toungoo General Hospital

Funding

Toungoo General hospital

Disclosure

All authors have declared no conflicts of interest.