428P_PR - Domestic cooking fuel as a risk factor for lung cancer in women - A case control study

Date 18 December 2016
Event ESMO Asia 2016 Congress
Session Poster lunch
Topics Non-Small Cell Lung Cancer
Aetiology, Epidemiology, Screening and Prevention
Presenter Asmin Sha
Citation Annals of Oncology (2016) 27 (suppl_9): ix134-ix135. 10.1093/annonc/mdw592
Authors A. Sha
  • General Pathology, al iqbal hospital and research centre, 679386 - thrissur/IN



Tobacco smoking is the most common risk factor for lung cancer. But a significant proportion of lungcancer occurs in non-smokers. Indoor pollution due to domestic fuels has been recently implicated asa causative agent in lung cancer especially in women. We conducted a case control study to find outthe role of Domestic Cooking Fuel as a risk factor for Lung Cancer in Indian women.


In a case control study 67 women with proven lung cancer were recruited. Forty-six females having anon-malignant respiratory disease constituted the control group. The patients and controls wereasked about the exposure in various cooking fuels using a questionnaire.


There were 50(74.6%) non-smokers and 17(25.4%) smokers among the female cancer cases(p = 0.016). Adenocarcinoma was the commonest histological type of malignancy (n = 26, 38.8%) in the whole group and was the predominant form in the non-smoking females. Tobacco smoking was the most important risk factor for lung cancer with OR of 4.87 (95% CI, 1.34-17.76). Among non-smokers out of all the cooking fuels the risk of development of lung cancer was highest for biomass fuel exposurewith an odds ratio of 5.33 (95%, CI 1.7-16.7). Use of mixed fuels was associated with a lesser risk(OR = 3.04, 95%, CI 1.1-8.38).


This study indicated that domestic cooking fuel exposure is an important risk factor in the causation of lung cancer among women in addition of exposure to tobacco smoke.

Clinical trial indentification


Legal entity responsible for the study



Al Iqbal Hospital and Research Centre


All authors have declared no conflicts of interest.