489P - Decrease in Palliative Performance Scale score during 1 week predicts survival in advanced cancer patients

Date 18 December 2016
Event ESMO Asia 2016 Congress
Session Poster lunch
Topics Palliative Care
Presenter SeokJoon Yoon
Citation Annals of Oncology (2016) 27 (suppl_9): ix157-ix160. 10.1093/annonc/mdw595
Authors S. Yoon
  • Family Medicine, Chungnam National University Hospital, 35015 - Daejeon/KR

Abstract

Background

Palliative Performance Scale (PPS) is a widely-used tool for measuring performance status of patients in palliative care settings. PPS is also known as a good prognostic tool for estimating survival. Recently, there were some studies announcing possibility of changes in PPS score as a prognostic tool. We aimed to investigate if a decrease in PPS score during 1 week predicts survival in advanced cancer patients of South Korea.

Methods

This study was prospective cohort study. Subjects were 73 patients admitted in Chungnam National University Hospital, South Korea from August 2015 till January 2016. PPS was measured at admission and 1 week later. Survival time was calculated as days from enrollment to death during admission. Kaplan-Meier survival curves were drawn for 3 groups (0%, < 50%, ≥ 50% decrease comparing initial PPS score). Cox regression analysis was performed after adjusting age, sex, diagnosis, treatment history and initial PPS score.

Results

Survival times of 0%, < 50% and ≥ 50% decrease comparing initial PPS score were 27.00±7.85, 14.00±3.73 and 10.00±1.35 days, respectively (p 

Conclusions

The greater decrease in PPS score during 1 week predicts the shorter survival time.

Clinical trial indentification

Legal entity responsible for the study

N/A

Funding

Chungnam National University Hospital

Disclosure

All authors have declared no conflicts of interest.