160P - The role of preoperative breast magnetic resonance (MR) imaging for surgical decision in patients with triple-negative breast cancer

Date 10 October 2016
Event ESMO 2016 Congress
Session Poster display
Topics Breast Cancer
Presenter Taek Ju Kwon
Citation Annals of Oncology (2016) 27 (6): 43-67. 10.1093/annonc/mdw364
Authors T.J. Kwon1, H.Y. Park1, J.H. Jung1, W.W. Kim1, S.O. Hwang1, Y.S. Chae2, S.J. Lee2, J. Park3, J.H. Chung1, J. Lee1
  • 1Department Of Surgery, Kyungpook National University School of Medicine, 41404 - Daegu/KR
  • 2Department Of Hematology/oncology, Kyungpook National University School of Medicine, 41404 - Daegu/KR
  • 3Department Of Pathology, Kyungpook National University School of Medicine, 41404 - Daegu/KR

Abstract

Background

Several reliable randomized studies do not recommend routine preoperative breast MR imaging for patients with breast cancer. However, because the principle of MR imaging is based on the dynamics of contrast enhancement, a specific biologic subgroup of tumors should sensitively respond to the imaging process.

Methods

From 2008 to 2013, 918 eligible patients with breast cancer underwent breast surgery and were divided into two groups based on preoperative breast MR findings: patients in whom the surgical plan was changed and those in whom the surgical plan remained unchanged. We investigated the changing patterns of breast surgery based on routine mammography, ultrasound, and preoperative breast magnetic resonance (MR) findings and analyzed the association between additional suspicious lesions on breast MR imaging and clinicopathologic factors.

Results

Additional suspicious breast lesions were detected on preoperative MR imaging in 104 cases (11.3%), and the surgical strategy was changed as the final decision in 97 cases (10.6%). There was no difference between oncologic results between two groups. However, the triple-negative breast cancer (TNBC) was significantly associated with changing of the surgical strategy based on breast MR findings (P = 0.048).

Conclusions

Additional preoperative breast MR imaging may be helpful in surgical decision for patients with TNBC.

Legal entity responsible for the study

Department of Surgery, Kyungpook National University School of Medicine

Funding

Department of Surgery, Kyungpook National University School of Medicine

Disclosure

All authors have declared no conflicts of interest.