1356P - Short-term quality of life changes after surgery in elderly (>65 years) patients with breast cancer using the medical outcomes study short form (MO...
Date | 09 October 2016 |
Event | ESMO 2016 Congress |
Session | Poster display |
Topics | Surgical Oncology Therapy Radiation Oncology |
Presenter | Franco Lumachi |
Citation | Annals of Oncology (2016) 27 (6): 469-473. 10.1093/annonc/mdw386 |
Authors |
F. Lumachi1, L. Di Gennaro2, P. Ubiali3, S.M.M. Basso3
|
Abstract
Background
Elderly patients with breast cancer (BC) usually present a reduction of their quality of life (QoL) both before and after surgery compared to younger patients. The short-form (SF-36) of the Medical Outcomes Study (MOS) questionnaire has long been used in clinical practice for patient population survey and healthy policy evaluation. The aim of this study was to evaluate the postoperative health-related QoL between elderly and young patients after breast-conserving surgery in patients with early (N0) BC using the MOS-SF-36 questionnaire.
Methods
Sixty-two consecutive patients (60.8 ± 9.9 years) with confirmed pT1-2 N0 M0 BC requiring conservative surgery were prospectively enrolled in the study. There were 36 (58.1%) elderly (>65 years of age) and 26 (41.9%) nonelderly patients. Informed consent was obtained from each participant. The day before discharge after surgery, all patients were asked to report their functional limitations and health-related status by filling the following sections of the MOS-SF-36 (No. of items): bodily pain (2), emotional role functioning (3), general health perceptions (5), mental health (5), physical functioning (10), physical role functioning (4), social role functioning (2), vitality (4).
Results
The results are reported in the Table. In general, the health-related QoF after surgery was similar in both groups. However, the scores related to bodily pain (64.3 ± 21.2 vs. 53.1 ± 16.3, p = 0.03), physical functioning (66.3 ± 18.2 vs. 56.3 ± 11.7, p = 0.02) and vitality (56.7 ± 13.6 vs. 50.1 ± 8.7, p = 0.03) reported by younger patients were higher than that reported by the elderly.
Parameters | ≤65 years | >65 years | p-value |
---|---|---|---|
Number of patients | 36 (58.1%) | 26 (41.9%) | - |
Median age (range) | 59 (35-65) | 67 (66-77) | - |
Bodily pain | 64.3 ± 21.2 | 53.1 ± 16.3 | 0.03 |
Emotional role functioning | 62.7 ± 18.4 | 60.5 ± 12.3 | 0.59 |
General health perceptions | 61.6 ± 12.3 | 58.3 ± 11.4 | 0.29 |
Mental health | 59.3 ± 16.4 | 57.1 ± 18.6 | 0.62 |
Physical functioning | 66.3 ± 18.2 | 56.3 ± 11.7 | 0.02 |
Physical role functioning | 72.3 ± 18.3 | 66.7 ± 15.4 | 0.21 |
Social role functioning | 61.6 ± 19.3 | 59.3 ± 14.1 | 0.61 |
Vitality | 56.7 ± 13.6 | 50.1 ± 8.7 | 0.03 |
Conclusions
The elderly are more sensitive to physical pain and exhibit a reduced vitality after surgery than younger patients. It can be hypothesized that they are worried by the problems that will occur after discharge.
Legal entity responsible for the study
University of Padua
Funding
University of Padua
Disclosure
All authors have declared no conflicts of interest.