1502P - Insomnia prevalence in an oncology patient population: an Irish tertiary referral centre experience

Date 09 October 2016
Event ESMO 2016 Congress
Session Poster display
Topics Supportive measures
Presenter Emily Harrold
Citation Annals of Oncology (2016) 27 (6): 497-521. 10.1093/annonc/mdw390
Authors E.C. Harrold1, A.F. Idris2, N.M. Keegan3, L. Corrigan4, M.Y. Teo5, S.T. Lim6, E. Duff6, M. O Donnell6, J. Kennedy7, D. O'Donnell8, S. Sukor4, C. Grant4, D. Gallagher4, S. Collier2, T. Kingston2, A.M. O'Dwyer2, S. Cuffe4
  • 1Dept Medical Oncology, Mater Hospital, 0000 - Dublin/IE
  • 2Department Of Medical Oncology, St James's Hospital, 8 - Dublin/IE
  • 3Medical Oncology, Beaumont Hospital, Dublin/IE
  • 4Medical Oncology, St James's Hospital, Dublin/IE
  • 5Medical Oncology, Memorial Sloan Kettering Cancer Center, NY 10065 - New York/US
  • 6Medicine, Trinity College Dublin, Dublin 2 - Dublin/IE
  • 7Medical Oncology, St James's Hospital, 8 - Dublin/IE
  • 8Haematology Oncology Day Care Centre, St James's Hospital, 8 - Dublin/IE

Abstract

Background

NCCN survivorship guidelines recommend dedicated sleep assessment reflecting its association with increased symptom distress scores and mortality Reported insomnia prevalence in the general Irish population is 15%; reported prevalence internationally amongst new or recently diagnosed cancer patients varies from 23-50%. Insomnia prevalence has not been quantified in an Irish oncology cohort.

Methods

With ethical approval an 8 page questionnaire was prospectively administered to ambulatory cancer patients aged ≥ 18 attending a tertiary referral centre. Pre-specified criteria for insomnia syndrome (IS) combined those of International Classification of Sleep Disorders and DSM-IV. The Hospital Anxiety and Depression scale (HADS-D/A) was used to screen for depression and anxiety as confounding variables. Logistical regression model was used for analysis.

Results

Response rate was 87% (294/337). Median respondent age was 55-64.80% were female. Breast (37%), colorectal (13%) and lung (12.2%) were the most common cancer subtypes. 62% reported sleep disturbance after diagnosis.33% met IS criteria. 60% reported moderate/severe insomnia related distress, 23% a significant impact on physical function. 45% who did not meet criteria had ≥1 of 4 critical features. On univariate analysis female sex, age

Conclusions

Insomnia prevalence in this Irish cohort is comparable to that previously reported and sleep assessment is justified. Alcohol is a modifiable risk factor independently predicting IS. HADS-D/A ≥11 increased OR of IS demonstrating additional utility of this scale. A patient education leaflet on sleep management is in progress to incorporate and reinforce our findings

Clinical trial identification

Legal entity responsible for the study

Dr Emily Harrold

Funding

N/A

Disclosure

All authors have declared no conflicts of interest.