110O - High-dose radiation therapy based on normal tissue constraints with concurrent chemotherapy improves survival of patients with unresectable stage I...

Date 12 April 2018
Event ELCC 2018 European Lung Cancer Congress
Session Limitations and advances of thoracic radiotherapy
Topics Anti-Cancer Agents & Biologic Therapy
Lung and other Thoracic Tumours
Surgery and/or Radiotherapy of Cancer
Presenter Baosheng Li
Citation Journal of Thoracic Oncology (2018) 13 (supp_4): S1-S139.
Authors B. Li, Q. Zhao, M. Liu
  • Radiation Oncology, Shandong Cancer Hospital, Jinan/CN


RTOG0617 found higher radiation dose does not benefit patients with unresectable stage III non-small cell lung cancer (NSCLC). To investigate the potential benefit of individual isotoxic dose escalation based on normal tissue constraints (NTC), hypothesizing that high-dose radiation therapy would be superior to standard-dose in concurrent chemoradiotherapy for unresectable stage III NSCLC.