53P - Transcutaneous electrical acupoint stimulation ameliorates chemotherapy-induced bone marrow suppression in lung cancer patients

Date 15 April 2016
Event European Lung Cancer Conference 2016 (ELCC) 2016
Session Poster lunch
Topics Lung and other Thoracic Tumours
Translational Research
Presenter Li Hou
Citation Journal of Thoracic Oncology (2016) 11 (supplement 4): S57-S166. S1556-0864(16)X0004-4
Authors L.L. Hou1, F. Gu2, C. Zhou3
  • 1Nursing Department, Shanghai Pulmonary Hospital, Tongji University, 200433 - Shanghai/CN
  • 2Respiratory Department, Shanghai Pulmonary Hospital, Tongji University, 200433 - Shanghai/CN
  • 3Oncology, Shanghai Pulmonary Hospital, Tongji University, 200433 - Shanghai/CN

Abstract

Background

TCM syndrome typing of chemotherapy-induced bone marrow suppression is Qi and blood deficiency and Qi and Yin deficiency [15]. According to the TCM channel and collateral theory, Dazhui (DU14), Geshu (BL17), Zusanli (ST36), Sanyinjiao (SP6), and Hegu (LI4) play a role in enriching blood and treating leucopenia. Although the literature reports no incompatibility between these acupoints, their combined effects have not been studied yet. The objective is to investigate the effect of percutaneous electrical stimulation on chemotherapy-induced bone marrow suppression in patients with lung cancer.

Methods

From December 2014 to August 2015, one hundred ninety-one non-small cell lung cancer patients with chemotherapy naive were randomly divided into transcutaneous electrical acupoint stimulation (TEAS) group, medication group, and control group. Patients with TEAS group received electrical stimulation of acupoints including Dazhui (DU14), Geshu (BL17), Zusanli (ST36), Sanyinjiao (SP6), and Hegu (LI4), the medication group was treated by oral administration of prophylactic agents, and the control group received routine nursing care. The primary end point was the blood routine indexes and secondary end point was the degree of comfort.

Results

The white blood cell in the TEAS group was significantly higher than the control group on day 8 and day 14 (P 

Conclusions

Percutaneous electrical stimulation of acupoints could prevent chemotherapy-induced bone marrow suppression in lung cancer patients and ensure a smooth continuation of chemotherapy.

Clinical trial identification

Legal entity responsible for the study

Lili Hou

Funding

Shanghai Health Talent Development Fund

Disclosure

All authors have declared no conflicts of interest.