Moving to the clinic: A progress in PD-1 inhibition in advanced melanoma

Speaker: Caroline Robert

C. Robert discusses PD-1 blockade in advanced melanoma, including CheckMate 067 and 069 studies where response rate and progression-free survival are better with a combination of anti-PD-1 and anti-CTLA4 blockade. As this combination leads to more toxicities, she speculates on the potential cases where it could be used.

Discussion Points

  • PD-1 inhibition improves patient survival in advanced melanoma
  • CheckMate 067 and CheckMate 069: Promising results