Landscape of mutations in the MAPK pathway

Speaker: Richard Marais

R. Marais explores a spectrum of mutations in the MAPK pathway, involving 3 genes and their associations with particular cancer types. He digs into profound discussion of rare, private mutations, as well as the problems of success in targeting treatments.

Discussion Points

  • What is the MAPK pathway? Which mutations are associated to this pathway?
  • Rare mutations in rare cancers: Why are they important to consider?
  • What are the prospects for the future in clinical practice?